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College of Arts & Sciences

Shiyong Wu

Dr. Shiyong Wu


Chemistry & Biochemistry
Clippinger 249A

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Ph.D., University of Nebraska (Chemistry)

Research Website

Publications (2014-18)

  1. Huizhi Zhao and Shiyong Wu*. The Effect of Endothelial Cells on UVB-induced DNA Damage and Transformation of Keratinocytes In 3D Polycaprolactone Scaffold Co-culture System. Photochem. & Photobio. 2018 Aug 30. [Epub ahead of print]
  2. Shiyong Wu* and Genji Imokawa. To be or not to be Photopigmented, that is the Question. An Introduction to the Special Issue dedicated to Photopigmentation and Melanoma. Photochem. & Photobio. 2018 May;94(3):407-408
  3. Weichao Sun, Yi Liao, Qian Yi, Shiyong Wu, Liling Tang*, Lingying Tong *. The Mechanism of CIRP in Regulation of STAT3 Phosphorylation and Bag-1/S Expression Upon UVB Radiation. Photochem. & Photobio. 2018 Nov;94(6):1234-1239
  4. Lingying Tong* and Shiyong Wu. The Mechanisms of Carnosol in Chemoprevention of Ultraviolet B-Light-Induced Non-Melanoma Skin Cancer Formation. Scientific Reports 2018 Feb 23;8(1)3574
  5. Lingying Tong* and Shiyong Wu. The Mechanisms of Carnosol in Chemoprevention of Ultraviolet B-Light-Induced Non-Melanoma Skin Cancer Formation. Scientific Reports 2018 Feb 23;8(1)3574
  6. Tingyang Zhou, Lanchun Lu, Shiyong Wu, and Li Zuo*. Effects of Ionizing Irradiation on Diaphragmatic Skeletal Muscle. Front Physiol. 2017 Jul 25;8:506
  7. Yi Liao, Lingying Tong, Liling Tang*, Shiyong Wu*. The Role of Cold-inducible RNA binding protein (CIRP) in Cell Stress Response.  (Mini Review). International Journal Of Cancer. 2017 Dec 1;141(11):2164-2173.
  8. Qian Yi, Jianguo Feng, Ling He, Rongxue Wan, Hui Zeng, Li Yang, Shiyong Wu, Liling Tang*. The structure-function relationships of insulin-linke growth factor 1 Ec in C2C12 cells. Cell Adh. Migr. 2017 May 4: 1-9.
  9. Qiong Wu and Shiyong Wu*. The role of lipid raft translocation of prohibitin in regulation of Akt and Raf-protected apoptosis of HaCaT cells upon ultraviolet B irradiation. Mol. Carcinogenesis 2017 Jul;56(7):1789-1797.
  10. Liuyi Dong, Ye Yuan, Cynthia Opansky, Yiliang Chen, Irene Aguilera- Barrantes, Shiyong Wu, Rong Yuan, Qi Cao, Yee Chung Cheng, Daisy Sahoo, Roy L. Silverstein, Bin Ren*. Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling. Oncotarget. 2017 Apr 4;8(14):22550-22562.
  11. Reetobrata Basu, Shiyong Wu, John J Kopchick*. Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways. Oncotarget Mar 28;8(13):21579-21598.
  12. Reetobrata Basu, Nicolas Madama-Baumgaertel, Shiyong Wu, John J Kopchick*. Growth hormone receptor (GHR) knockdown sensitizes human melanoma cells to chemotherapy by attenuating expression of ABC drug efflux pumps. Horm. Cancer. 2017 Jun;8(3):143-156.
  13. Yi Liao, Jianguo Feng, Yi Zhang, Liling Tang*, Shiyong Wu*. The Mechanism of CIRP In Inhibition of Keratinocytes Growth Arrest and Apoptosis Following Low Dose UVB Radiation. Mol. Carcinogenesis 2017 Jun;56(6):1554-1569
  14. Dongqing Zhang, Tingyang Zhou, Feng He, Yi Rong, Shin Hee Lee, Shiyong Wu, Li Zuo* Reactive oxygen species formation and bystander effects in gradient irradiation on human breast cancer cells. Oncotarget. 2016 Jul 5;7(27):41622-41636
  15. Ye Yuan, Larry S. Wu Siqi Shen, Shiyong Wu*, and Monica M. Burdick*. Effect of alpha 2,6 Sialylation on Integrin-mediated Adhesion of Breast Cancer Cells to Fibronectin and Collagen IV. Life Sciences (2016) 149: 138-145.
  16. Qiuling Zheng, Hao Zhang, Lingying Tong, Shiyong Wu and Hao Chen* Probing protein 3D structures and conformational changes using electrochemistry-assisted isotope labeling cross-linking mass spectrometry. J. Am. Soc. Mass Spectrom. (2016) May;27(5):864-75
  17. Jianguo Feng, Li Li, Lingying Tong, Liling Tang* and Shiyong Wu*. The Involvement of Splicing Factor hnRNP A1 in UVB-Induced Alternative Splicing of hdm2. Photochem. & Photobio. 2016 92: 318-324.
  18. Lingying Tong, Chia-chen Chuang Shiyong Wu* and Li Zuo*. Reactive oxygen species in redox cancer therapy. Cancer Lett. 2015 Oct 10;367(1):18-25.
  19. Weiwei Yuan, Ye Yuan, Tao Zhang* and Shiyong Wu*. Role Of Bmi-1 In Regulation of Ionizing Irradiation-Induced Epithelial-Mesenchymal Transition and Migration Of Breast Cancer Cells. Plos One. 2015 March 3; 10(3).
  20. Lingying Tong and Shiyong Wu*. ROS and p53 in Regulation of UVB-induced hdm2 Alternative Splicing. Photochem. & Photobio. 2015 Jan;91(1):221-224.
  21. Lingying Tong, Ye Yuan and Shiyong Wu*. Therapeutic microRNAs targeting the NF-kappa B Signaling Circuits of Cancers. Adv. Drug Dis. Rev. 2015 Jan;81C:1-15.
  22. Xiaozhuo Chen, Yanrong Qian, Shiyong Wu*. The Warburg Effect: Evolving Interpretations Of An Established Concept. Free Radical Biology & Medicine. 2015 (7) 253-63.
  23. Qiuling Zheng, Hao Zhang, Lingying Tong, Shiyong Wu, Hao Chen*.  A New Cross-Linking Electrochemical Mass Spectrometry for Probing Protein 3D-Structures. Anal. Chem. 2014 Sep 16;86(18):8983-91.
  24. Huiwen Cheng, Lei Wang, Molly Mollica, Anthony T Re, Shiyong Wu*, Li Zuo*. Nitric oxide in cancer metastasis. Cancer Lett. 2014 353(1): 1–7.
  25. Lingying Tong and Shiyong Wu*. The Role of Constitutive Nitric Oxide Synthase in UVB-induced NF-κB Activity. J. Biol. Chem. 2014 Sep 19;289(38):26658-68.
  26. Shin Hee Lee, Huiwen Cheng, Ye Yuan, and Shiyong Wu*. Regulation of ionizing radiation-induced adhesion of breast cancer cells to fibronectin by alpha5beta1 integrin.  Radiat Res. 2014 Jun;181(6):650-8.
  27. Yanrong Qian, Xuan Wang, Yi Liu, Yunsheng Li, Robert Colvin, Lingying Tong, Shiyong Wu, Xiaozhuo Chen*. Extracellular ATP-induced intracellular ATP increase in cancer cells is mediated by macropinocytosis and contributes to cancer cell survival and drug resistance. Cancer Lett. 2014 Sep 1;351(2):242-51.
  28. Huiwen Cheng, Lei Wang, Molly Mollica, Anthony T. Re, Shiyong Wu*, and Li Zuo*. Nitric oxide in cancer metastasis. (Review) Cancer Lett. 2014 Oct 10;353(1):1-7.
  29. Ye Yuan, Michelle L Duff, Dawn L Sammons*, Shiyong Wu. Retrospective chart review of skin cancer presence in the wide excisions. World J Clin Cases 2014 March 16; 2(3): 52-56.
  30. Oliver L. Carpenter and Shiyong Wu*. Regulation of MSK-1-mediated NF-kB Activation Upon UVB Irradiation. Photochem. & Photobio. (2014).  90: 155-61.
  31. Weiwei Yuan, Xuelin Zhang, Yu Xu, Shasha Li, Yide Hu*, and Shiyong Wu*. Role Of HOXB7 In Regulation Of Progression And Metastasis Of Human Lung Adenocarcinoma. Mol. Carcinogenesis (2014) 53(1):49-57.

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